Mannan 1,4-mannobiosidase (, 1,4-β-D-mannan mannobiohydrolase, exo-β-mannanase, exo-1,4-β-mannobiohydrolase) is an enzyme with systematic name 4-β-D-mannan mannobiohydrolase. It catalyses the hydrolysis of (1→4)-β-D-mannosidic linkages in (1→4)-β-D-mannans, to remove successive mannobiose residues from the non-reducing chain ends.

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