Van Hooydonck is a Dutch surname. It can refer to:
Edwig Van Hooydonck (born 1966), Belgian cyclist (born 1964), Belgian cyclist Nathan Van Hooydonck (born 1995), Belgian cyclist, son of Gino and nephew of Edwig
See also Van Hooydonk, van Hooijdonk Paul Van Hoeydonck (1925–2025), Belgian sculptor and painter