Van Hoesen is a surname. Notable people with the surname include:

Beth Van Hoesen (1926–2010), American artist Henry Bartlett van Hoesen, (1885–1965), American librarian at Brown University K. David van Hoesen (1926–2016), bassoonist Peter Van Hoesen (born 1970), Belgian musician and composer

See also Jan Van Hoesen House, a house in Columbia County, New York, United States