Van Hooijdonk or van Hooydonk is a Dutch toponymic surname Hooijdonk/Hooydonk is an archaic spelling of "Hooidonk", a village between Nuenen and Son, North Brabant. Notable people with the surname include:

Adrian van Hooydonk (born 1964), Dutch automobile designer Jeffrey van Hooydonk (born 1977), Belgian racing driver Johannes van Hooydonk (born 1782), Dutch clergyman Pierre van Hooijdonk (born 1969), Dutch footballer

See also Van Hooydonck