The enzyme maltose-6′-phosphate glucosidase () catalyzes the following chemical reaction:
The enzyme characterised from Fusobacterium mortiferum hydrolyses maltose 6'-phosphate to glucose 6-phosphate and D-glucose. The enzyme also hydrolyses other 6-phospho-α-D-glucosides. A process to produce tyrosine has been developed which involves optimising this and other enzymes by metabolic engineering.
It belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. It participates in starch and sucrose metabolism.
Nomenclature The systematic name of this enzyme class is maltose-6′-phosphate 6-phosphoglucohydrolase. This enzyme is also called phospho-α-glucosidase.
Structural studies As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code .
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