NMN nucleosidase () is an enzyme characterised from Escherichia coli that catalyzes the hydrolysis of nicotinamide mononucleotide (NMN) to D-ribose 5-phosphate and nicotinamide:
This enzyme is a hydrolase, specifically a glycosylase that hydrolyses N-glycosyl compounds. The systematic name of this enzyme class is nicotinamide-nucleotide phosphoribohydrolase. Other names in common use include NMNase, nicotinamide mononucleotide nucleosidase, nicotinamide mononucleotidase, NMN glycohydrolase, and NMNGhase.
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