Inosine nucleosidase () is an enzyme that catalyzes the chemical reaction
The enzyme characterised from Escherichia coli and fish muscle hydrolyses the purine nucleoside, inosine, to hypoxanthine and D-ribose.
This enzyme is a hydrolase, specifically a glycosylase that hydrolyses N-glycosyl compounds. The systematic name of this enzyme class is inosine ribohydrolase. Other names in common use include inosinase, and inosine-guanosine nucleosidase.
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