Deir ez-Zor District () is a district of the Deir ez-Zor Governorate in northeastern Syria. The administrative centre is the city of Deir ez-Zor. At the 2004 census, the district had a population of 492,434.

Subdistricts The district of Deir ez-Zor is divided into seven subdistricts or nawāḥī (population as of 2004): Deir ez-Zor Subdistrict (ناحية دير الزور): population 239,196. Al-Kasrah Subdistrict (ناحية الكسرة): population 63,226. Al-Busayrah Subdistrict (ناحية البصيرة): population 40,236. Al-Muhasan Subdistrict (ناحية الموحسن): population 35,113. Al-Tabni Subdistrict (ناحيةالتبني): population 48,393. Khasham Subdistrict (ناحية خشام): population 28,718. Al-Suwar Subdistrict (ناحية الصور): population 37,552.

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