Naidoo is a South African Indian surname. It is an alternative spelling of Naidu. Notable people with the surname include:

Ama Naidoo (1908–1993), South African anti-apartheid activist Anand Naidoo, South African television anchor Beverley Naidoo, South African children's author Euvin Naidoo, South African businessman Indira Naidoo (born 1968), Australian author Indira Naidoo-Harris, South African-born Canadian politician Jay Naidoo (born 1954), South African trade unionist Kasturi "Kass" Naidoo (born 1975 or 1976) a female South African cricket commentator. Kesivan Naidoo (born 1979), South African drummer Kimeshan Naidoo (born 1991), South African entrepreneur and engineer Kumi Naidoo (born 1965), South African human rights activist Leigh-Ann Naidoo (born 1976), South African beach volleyball player Manna Naidoo (1948–2022), South African politician Naransamy Roy Naidoo (1901–1953), South African activist Ravi Naidoo, South African designer Shanti Naidoo, South African anti-apartheid activist Shashi Naidoo (born 1980), South African actress Stephen Naidoo (1937–1989), South African Roman Catholic archbishop Thambi Naidoo (1875–1933), South African politician Vassi Naidoo (1955–2021), South African businessman Xavier Naidoo (born 1971), German singer

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