Chromosome 9 is one of the 23 pairs of chromosomes in humans. Humans normally have two copies of this chromosome, as they normally do with all chromosomes. Chromosome 9 spans about 138 million base pairs of nucleic acids (the building blocks of DNA) and represents between 4.0 and 4.5% of the total DNA in cells.

Genes Number of genes These are some of the gene count estimates of human chromosome 9. Because researchers use different approaches to genome annotation, their predictions of the number of genes on each chromosome varies (for technical details, see gene prediction). Among various projects, the collaborative consensus coding sequence project (CCDS) takes an extremely conservative strategy. So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes.

Estimated by Protein-coding genes Noncoding RNA genes Pseudogenes Source Release date CCDS 739 — — 2016-09-08 HGNC 749 246 590 2017-05-12 Ensembl 775 788 663 2017-03-29 UniProt 812 — — 2018-02-28 NCBI 822 830 738 2017-05-19

Gene list

The following is a partial list of genes on human chromosome 9. For a complete list, see the link in the infobox on the right.

Diseases and disorders The following diseases are some of those related to genes on chromosome 9:

acytosiosis ALA-D deficiency porphyria Amyotrophic lateral sclerosis citrullinemia

Coronary artery disease chronic myelogenous leukemia (t9;22 - the Philadelphia chromosome) Diaphyseal Medullary Stenosis with Malignant Fibrous Histiosytoma (DMS-MFH, Hardcastle syndrome) Ehlers-Danlos syndrome familial dysautonomia Friedreich ataxia Frontotemporal dementia galactosemia Gorlin syndrome or nevoid basal cell carcinoma syndrome hereditary hemorrhagic telangiectasia lethal congenital contracture syndrome nail-patella syndrome (NPS) nonsyndromic deafness OCD polycythemia vera porphyria primary hyperoxaluria STXBP1 Tangier disease tetrasomy 9p thrombotic thrombocytopenic purpura trisomy 9 tuberous sclerosis VLDLR-associated cerebellar hypoplasia

Cytogenetic band

+ G-bands of human chromosome 9 in resolution 850 bphsGenome Decoration Page, NCBI. Ideogram data for Homo sapience (850 bphs, Assembly GRCh38.p3). Last update 2014-06-03. Retrieved 2017-04-26. Chr. Arm"p": Short arm; "q": Long arm. BandFor cytogenetic banding nomenclature, see article locus. ISCNstartThese values (ISCN start/stop) are based on the length of bands/ideograms from the ISCN book, An International System for Human Cytogenetic Nomenclature (2013). Arbitrary unit. ISCNstop Basepairstart Basepairstop Staingpos: Region which is positively stained by G banding, generally AT-rich and gene poor; gneg: Region which is negatively stained by G banding, generally CG-rich and gene rich; acen Centromere. var: Variable region; stalk: Stalk. Density 9 p 24.3 0 127 gneg 9 p 24.2 127 268 gpos 25 9 p 24.1 268 451 gneg 9 p 23 451 677 gpos 75 9 p 22.3 677 846 gneg 9 p 22.2 846 987 gpos 25 9 p 22.1 987 1085 gneg 9 p 21.3 1085 1297 gpos 100 9 p 21.2 1297 1395 gneg 9 p 21.1 1395 1621 gpos 100 9 p 13.3 1621 1917 gneg 9 p 13.2 1917 2030 gpos 25 9 p 13.1 2030 2171 gneg 9 p 12 2171 2312 gpos 50 9 p 11.2 2312 2523 gneg 9 p 11.1 2523 2650 acen 9 q 11 2650 2876 acen 9 q 12 2876 3468 gvar 9 q 13 3468 3609 gneg 9 q 21.11 3609 3792 gpos 25 9 q 21.12 3792 3876 gneg 9 q 21.13 3876 4060 gpos 50 9 q 21.2 4060 4229 gneg 9 q 21.31 4229 4440 gpos 50 9 q 21.32 4440 4638 gneg 9 q 21.33 4638 4835 gpos 50 9 q 22.1 4835 5074 gneg 9 q 22.2 5074 5173 gpos 25 9 q 22.31 5173 5314 gneg 9 q 22.32 5314 5455 gpos 25 9 q 22.33 5455 5638 gneg 9 q 31.1 5638 5892 gpos 100 9 q 31.2 5892 6005 gneg 9 q 31.3 6005 6146 gpos 25 9 q 32 6146 6456 gneg 9 q 33.1 6456 6681 gpos 75 9 q 33.2 6681 6822 gneg 9 q 33.3 6822 6949 gpos 25 9 q 34.11 6949 7217 gneg 9 q 34.12 7217 7302 gpos 25 9 q 34.13 7302 7443 gneg 9 q 34.2 7443 7555 gpos 25 9 q 34.3 7555 7950 gneg

References

External links