Irausquin or Yrausquin is a surname. Notable people with the surname include:
Juancho Yrausquin, Netherlands Antillean banker and politician Juancho E. Yrausquin Airport, Saba, Netherlands Juan David Yrausquin, Aruban politician Maria Irausquin-Wajcberg, Aruban politician Percy Irausquin, Aruban-born Dutch fashion designer and couturier Víctor Vargas Irausquín, Venezuelan banker and businessman