Etherton is an English surname. Notable people with the surname include:
Penny M. Kris-Etherton, American dietitian Ralph Etherton (1904–1987), British barrister and politician Seth Etherton (born 1976), American baseball player and coach Terence Etherton, Baron Etherton (1951–2025), British judge and politician
See also Etherton, Illinois, an unincorporated community in Jackson County, Illinois, United States