Mühlemann is a surname of Swiss origin. Notable people with the surname include:
Benjamin Mühlemann (born 1979), Swiss politician Hans Rudolf Mühlemann (1917–1997), Swiss dentist and academic Lukas Mühlemann (born 1950), Swiss banker Regula Mühlemann (born 1986), Swiss operatic soprano
See also Morris E. Muhleman (1915–1998), American politician