Jayalath is both a given name and a surname. Notable people with the name include:
Jayalath Jayawardena (1953–2013), Sri Lankan medical doctor Jayalath Manoratne (1948–2020), Sri Lankan actor Jayalath Weerakkody, Sri Lankan air officer Dilan Jayalath (born 1997), Sri Lankan cricketer Dileepa Jayalath (born 1997), Sri Lankan cricketer Florida Jayalath (1936–2007), Sri Lankan actress Karunasena Jayalath (1928–1994), Sri Lankan newspaper editor