Huys is a surname. Notable people with this surname include:
Auguste-Léopold Huys (1871–1938), French missionary Mario Huys (born 1959), Belgian triathlete Modest Huys (1874–1932), Flemish painter Pieter Huys (c.1519–c.1584), Flemish Renaissance painter. Servaas Huys (1940–2016), Dutch politician Twan Huys (born 1964), Dutch journalist, television presenter and author