Aizpuru (also Aizpurúa and Aispurua) is a surname of Basque origin.misapellidos.com (in Spanish) Notable people with the surname include:
Natalia Aispurúa (born 20 December 1991), Argentine volleyball player. Iñaki Aizpurua (born 1970), Spanish retired footballer who played as a goalkeeper. Juana de Aizpuru (born 1933), Spanish art gallerist. Julián Elorza Aizpuru (1879–1964), Spanish politician. Manuela Sáenz y Aizpuru (1797–1856), Ecuadorian revolutionary. Mertxe Aizpurua, Spanish journalist and politician. Oier Aizpurua (1977), Spanish sprint canoer who competed in the early 2000s. Pilar Gonzalbo Aizpuru (born 1935), Spanish academic. Mario Mendoza Aizpuru (born 26 December 1950)
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