Dioguardi or DioGuardi is an Italian surname literally translating to . Notable people with the surname include:
Giovanni Dioguardi (1914–1979), best known as Johnny Dio, American labor racketeer Joe DioGuardi (born 1940), American politician Kara DioGuardi (born 1970), American singer-songwriter Nick Dioguardi (1932–2015), Italian-born American racing driver Pasta Dioguardi (born 1961), Argentine actor Patrizia Dioguardi, known as just Patrizia, Italian-Canadian singer Philippe DioGuardi (born 1961), Canadian tax lawyer