Knoepffler is a German occupational surname. The word is an orthographic variant of Knöpfler, "buttonmaker"."Knopfler", In: Dictionary of American Family Names (2 ed.), 2002 Notable people with the surname include:
Campari Knoepffler (born 1959), Nicaraguan swimmer Nikolaus Knoepffler (born 1962), German philosopher and theologian
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