Thrixopelma is a genus of South American tarantulas that was first described by Günter E. W. Schmidt in 1994. They are medium to large tarantulas, usually being 35mm to 60mm in body length.

Diagnosis Males can be distinguished by the presence of two crests in the palpal bulb. Females can be distinguished by the spermathecae, which is made up of two separate hypersclerotized receptacles. This genus also own type 3 urticating hairs, or both type 3 and 4.

Species it contains 8 species, found in South America: Thrixopelma aymara (Chamberlin, 1916) – Peru Thrixopelma cyaneolum Schmidt, Friebolin & Friebolin, 2005 – Peru Thrixopelma lagunas Schmidt & Rudloff, 2010 – Peru Thrixopelma longicolli (Schmidt, 2003) – Ecuador, Peru Thrixopelma nadineae Sherwood & Gabriel, 2022 - Ecuador Thrixopelma ockerti Schmidt, 1994 (type) – Peru Thrixopelma peruvianum (Schmidt, 2007) – Peru Thrixopelma pruriens Schmidt, 1998 – Chile

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