Pennacchi is a surname. Notable people with the surname include:
Andrea Pennacchi (born 1969), Italian actor Antonio Pennacchi (1950–2021), Italian writer Fulvio Pennacchi (1905–1992), Italian-Brazilian artist George Pennacchi, American economist Lucas Pennacchi (born 1960), Brazilian artist Pier Maria Pennacchi (1464—before 1515), Italian Renaissance painter
See also: Pennacchio (surname)