Mukasa is a surname. Notable people with the surname include:
Adolphus Ludigo-Mukasa (1861–1886), Ugandan Roman Catholic martyred for his faith Mukasa Mbidde (born 1973), Ugandan lawyer, human-rights activist, politician Ashe Mukasa (born 1952), former Ugandan football midfielder Basammula-Ekkere Mwanga II Mukasa (1868–1903), Kabaka of Buganda from 1884 until 1888 and from 1889 until 1897 Ham Mukasa (1868–1956), page in the court of Mutesa I of Buganda and later secretary to Apolo Kagwa Joseph Mukasa Balikuddembe (1860–1885), Ugandan Roman Catholic recognized as a martyr and saint by the Catholic Church Roger Mukasa, (born 1989), Ugandan cricketer Ruben Spartas Mukasa (1899–1982), religious reformer in Uganda Wilson Muruli Mukasa, Ugandan politician Joseph Mukasa Zuza (1955–2015), Roman Catholic bishop Nathan Mukasa (born 2004), Ugandan/Trinidadian businessman Mukasa (deity), Buganda god of prosperity, harvest, fertility, and health
See also Mukasura Mukhtasar Muklassa