The 1999–2000 Israel State Cup (, Gvia HaMedina) was the 61st season of Israel's nationwide football cup competition and the 46th after the Israeli Declaration of Independence.
The competition was won by Hapoel Tel Aviv who had beaten Beitar Jerusalem 4–2 on penalties after 2–2 in the final.
As Hapoel Tel Aviv won the double, Beitar Jerusalem qualified to the 2000–01 UEFA Cup, entering in the qualifying round.
Results Seventh Round Home teamScoreAway team
Byes: Hapoel Ironi Dimona, Hapoel Ironi Hod HaSharon, Hapoel Makr, Hapoel Nazareth Illit.
Intermediate Round Home teamScoreAway team
Eighth Round Home teamScoreAway team
Round of 16 Home teamScoreAway team
Quarter-finals Home teamScoreAway team
Semi-finals Home teamScoreAway team
Final
References 100 Years of Football 1906–2006, Elisha Shohat (Israel), 2006, pp. 310–11 Israel Cups 1999/2000 RSSSF