Henze is a German surname. Notable people with the surname include:

Albert Henze (1894–1979), German Wehrmacht general Frank Henze (born 1977), German slalom canoeist Gertrud Henze (1901–2014), a German supercentenarian Gregor Henze, German-American engineer Hans Werner Henze (1926–2012), German composer Jürgen Henze (born 1950), East German slalom canoeist Leon Henze (born 1992), German footballer Martin Henze (born 1981), a German astronomer and namesake of minor planet 6642 Henze Friedrich Wolfgang Martin Henze (1873 – 1956), a German chemist who first discovered vanadium-containing proteins known as vanabins in 1911 Matthias Henze, the Isla Carroll and Perry E. Turner Professor of Hebrew Bible and Early Judaism at Rice University in Houston Paul Bernard Henze (1924—2011), CIA officer and national security specialist Richard Henze (1895–1985), a highly decorated Oberst of the Reserves in the Wehrmacht during World War II Stefan Henze (1981–2016), German slalom canoeist

See also 6642 Henze, a minor planet named for German astronomer Martin Henze Henze Boekhout (1947–2024), Dutch artist/photographer