M7GpppN-mRNA hydrolase (, D10 protein, D9 protein, D10 decapping enzyme, decapping enzyme) is an enzyme with systematic name m7GpppN-mRNA m7GDP phosphohydrolase. This enzyme catalyses the following chemical reaction
m7G5'ppp5'-mRNA + H2O m7GDP + 5'-phospho-mRNA
Decapping of mRNA is essential in eukaryotic mRNA turnover. In humans, this type of enzyme activity has been reported for the proteins NUDT3, NUDT16, NUDT17, DCP1A, DCP1B, and DCP2.
References
External links