U8 snoRNA-decapping enzyme, also called nudix hydrolase 16, is an enzyme that in humans is encoded by the NUDT16 gene. This enzyme can function as a M7GpppN-mRNA hydrolase () and is the only reported inosine diphosphate phosphatase () in humans.
Function Has several functions, including RNA binding activity; metal ion binding activity; and pyrophosphatase activity. Involved in RNA metabolic process and positive regulation of cell cycle process. Located in cytoplasm; nucleolus; and nucleoplasm.
Inosine diphosphate phosphatase As a Inosine diphosphate phosphatase (), this enzyme can hydrolyzes IDP (and dIDP) as part of the following reaction: (d)IDP + H2O = (d)IMP + phosphate + H+
The human enzyme is also able to hydrolyze similar molecules, especially GDP and dGDP.
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