2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase (, ArfB) is an enzyme with systematic name 2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one amidohydrolase. It catalyses the hydrolysis of 2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and formic acid, which is the second step in riboflavin and 7,8-didemethyl-8-hydroxy-5-deazariboflavin biosynthesis in archaea:
The enzyme has been studied as part of the commercial production of riboflavin.
References
External links