N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase (, MshB) is an enzyme characterised from Mycobacterium with systematic name 1-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol acetylhydrolase. It catalyses the hydrolysis of 1D-myo-inositol 2-acetamido-2-deoxy-α-D-glucopyranoside to 1D-myo-inositol 2-amino-2-deoxy-α-D-glucopyranoside and acetic acid:
This enzyme mediates the rate limiting step in the mycothiol biosynthesis pathway. X-ray crystallography showed that the enzyme contains zinc.
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