Pancreatic elastase II (, pancreatic elastase 2) is an enzyme which in humans can encoded by the CELA2A or CELA2B genes. This enzyme catalyses the following chemical reaction
Preferential cleavage: Leu-, Met- and Phe-. Hydrolyses elastin
This peptidase is from the trypsin family. It is produced by the acinar cells of the pancreas in an inactive form called proelastase II which is subsequently activated by trypsin in the small intestines.
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