Biflaviolin synthase (, CYP158A2, CYP 158A2, cytochrome P450 158A2) is an enzyme with systematic name flaviolin,NADPH:oxygen oxidoreductase. This enzyme catalyses two related chemical reactions:
The reaction is an oxidative coupling of phenols which forms a dimer of the starting material. The alternative isomer, 3,8'-biflaviolin, is also producted. Biflaviolin synthase is a cytochrome P450 enzyme, isolated from the soil-dwelling bacterium Streptomyces coelicolor.
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