Flavonoid 3',5'-hydroxylase

Flavonoid 3',5'-hydroxylase ( was wrongly classified as in the past) is an enzyme with systematic name flavanone,NADPH:oxygen oxidoreductase. This enzyme catalyses the following chemical reaction

flavanone + 2 NADPH + 2 H+ + 2 O2 3',5'-dihydroxyflavanone + 2 NADP+ + 2 H2O (overall reaction) (1a) flavanone + NADPH + H+ + O2 3'-hydroxyflavanone + NADP+ + H2O (1b) 3'-hydroxyflavanone + NADPH + H+ + O2 3',5'-dihydroxyflavanone + NADP+ + H2O

Flavonoid 3',5'-hydroxylase is a heme-thiolate protein (P-450).

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