Vertefeuille is a surname. Notable people with the surname include:
Christine S. Vertefeuille (born 1950), American lawyer and judge Fabien Vanasse dit Vertefeuille (1850–1936), Canadian journalist, lawyer and politician Jeanne Vertefeuille (1932–2012), CIA officer who investigated Cold War spy Aldrich Ames
See also Francois Vertefeuille House, historic house in Wisconsin, United States