Vértiz is a surname. Notable people with the surname include:

Juan José de Vértiz y Salcedo (1719–1799), Spanish colonial politician Natalie Vértiz (born 1991), Peruvian beauty pageant winner and model Pedro Suárez Vértiz (born 1968), Peruvian singer-songwriter and guitarist Virginia Castlen Vértiz (born 1949), American researcher and humanitarian