Catherine Bruce may refer to:
Lady Catherine Bruce of Clackmannan (1696–1791), Scottish noblewoman Catherine Brudenell-Bruce (born 1984), English singer, also known as Bo Bruce Catherine Wolfe Bruce (1816–1900), American philanthropist Cathy Bruce (academic), Canadian academic and university administrator
See also Kate Bruce (1860–1946), American actress Katharine Bruce Glasier (1867–1950), English politician