Gilkyson is a surname. Notable people with the surname include:
Eliza Gilkyson (born 1950), American folk musician, daughter of Terry Gracie Gilkyson (born 2003), Canadian ice hockey player Terry Gilkyson (1916–1999), American folk singer, composer, and lyricist, father of Eliza and Tony Tony Gilkyson (born 1952), American musician, son of Terry Stephen R. Gilkyson, a Lieutenant Colonel of the 6th New Jersey in the American Civil War
See also Gilkes Gilston