CLN may refer to:
Computing and technology Class Library for Numbers, a free software project Computer Learning Network, a technical school (college) in Mechanicsburg, Pennsylvania; see YTI Career Institute Controlled natural language, a subset of a natural language that is obtained by restricting its grammar and vocabulary in order to reduce or eliminate ambiguity and complexity.
Politics and government Certificate of Loss of Nationality, an American form National Liberation Committee (), the underground political entity of Italian Partisans during the German occupation of Italy
Other Catamount Library Network, a library consortium in Vermont Chapeltown railway station, in South Yorkshire Credit-linked note, a security issued by a special purpose company or trust Sri Lanka (Ceylon), ITU country code
See also Genes related to neuronal ceroid lipofuscinosis: CLN3, CLN5, CLN6, CLN8