D-161 is a chemical known in research circles as a triple reuptake inhibitor. Although this compound has lent support to the inclusion of dopamine in the monoamine hypothesis of depression, D-161 has not been tested in clinical trials.

A more recent study was reported.

A couple of patents are also disclosed.Aloke K. Dutta, WO2005105075 (Wayne State University).Aloke K. Dutta, US8017791 (2011 to Wayne State University). Synthesis The synthesis of this agent has been reported.

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