Samuel Thomas may refer to:

Buzz Thomas (Samuel Thomas, born 1969), politician from the U.S. state of Michigan Samuel Bath Thomas (1855–1919), founder of Thomas' English muffins and bagels Samuel Bell Thomas (1868–1943), New York lawyer Samuel Thomas (priest) (1627–1693), English nonjuring clergyman and controversialist Samuel Russell Thomas (1840–1903), American capitalist and Union Army general Samuel Benjamin Thomas, Sierra Leonean entrepreneur and philanthropist Samuel Joyce Thomas, British barrister, colonial judge and politician

See also Sam Thomas (disambiguation)