Rustichelli is a surname. Notable people with the surname include:
Alida Rustichelli alias Alida Chelli (1943–2012), Italian actress and singer Carlo Rustichelli (1916–2004), Italian composer Dominique Rustichelli (born 1934), French soccer player Paolo Rustichelli (born 1953), Italian-American pianist, composer, and producer
See also 38541 Rustichelli, main-belt asteroid Rustichello da Pisa, 13th century Italian romance writer