Migliorini is an Italian surname. Notable people with the surname include:
Andrea Migliorini (born 1988), Italian footballer playing for Melbourne Heart Barry Migliorini (born 1966), American professional basketball coach Bruno Migliorini (1896–1975), Italian linguist and philologist Giovanni Migliorini (1931–1980), retired Italian professional football player Marco Migliorini (born 1992), Italian footballer playing for Salernitana Renato Migliorini (1926–2008), Brazilian physician, biomedical scientist, biochemist and full professor of physiology
See also 5246 Migliorini, Mars-crossing asteroid discovered on 26 July 1979