Mathes may refer to:
Given name Mathes Roriczer (1440–1493), German architect
Surname Ben Mathes, minister in the Presbyterian Church (USA) involved in providing health care in remote regions of the world Charles Mathes (born 1949), American author of mystery novels Harry Mathes (1882–1969), American painter in the New York art scene Lena B. Mathes (1861–1951), American educator, social reformer, and ordained minister Les Mathes, commune in the Charente-Maritime department in western France Merissa Mathes (born 1940), American actress and model Rob Mathes, American record producer, music arranger, composer, songwriter, and performer Simone Mathes (born 1975), German hammer thrower W. Michael Mathes (1936–2012), American historian and academic
Other uses Cheff v. Mathes (Del. 1964), case in the Delaware Supreme Court Curtis Mathes Corporation, North American electronics retailer based in Garland, Texas Elser-Mathes Cup, celebrates the first two-way contact by amateur radio between the Earth and Mars