The Marche regional election of 2005 took place on 3–4 April 2005.

Gian Mario Spacca (The Daisy, then Democratic Party) defeated Francesco Massi (Union of Christian and Centre Democrats, at the time, now member of The People of Freedom) by a landslide.

Results Candidates & parties votes votes (%) seatsreg. list seatsprov. lists Gian Mario Spacca499,38157.76420 The Olive Tree316,81640.12→15 Communist Refoundation Party49,9896.33→2 Party of Italian Communists31,3163.97→1 Federation of the Greens25,6663.25→1 UDEUR14,1721.79→1 Italy of Values11,1361.41→0 Civic Lists5,7800.73→0 Francesco Massi333,18138.54115 Forza Italia142,05817.99→8 National Alliance102,10712.93→5 Union of Christian and Centre Democrats57,2937.26→2 Lega Nord Marche6,8660.87→0 Michele Tiraboschi19,7782.29-- Christian Democracy10,8571.37→0 New PSI–PRI–PLI–PSDI–Others5,1250.65→0 Vincenzo Rosini12,2391.42-- Social Alternative10,0681.28→0 No Euro3900.05→0 Total864,579100.00535 Source: Ministry of the Interior