ST2 may refer to:

Ducati ST2, an Italian sport touring motorcycle ST2, the postcode district of the ST postcode area covering Bentilee, Abbey Hulton, and Bucknall ST2 receptor, or IL1RL1, an interleukin receptor protein ST2 cardiac biomarker, a novel biomarker of cardiac stress Sound Transit 2, a joint ballot measure to expand and improve Washington state's Puget Sound public transport system Star Trek II: The Wrath of Khan, a 1982 American science fiction film released by Paramount Pictures Star Trek Into Darkness, a 2013 film Starship Troopers 2: Hero of the Federation, second film in the Starship Troopers film series Zoda's Revenge: StarTropics II, a video game released only in North America in 1994 ST-2, a telecommunications satellite in geosynchronous orbit, launched in 2011

See also 2ST, radio station in NSW, Australia 2nd Street (disambiguation) STII (disambiguation) STT (disambiguation) STST (disambiguation)