The 1999–2000 Campionato Sammarinese di Calcio season was the 15th season since its establishment. It was contested by 16 teams, and S.S. Folgore/Falciano won the championship.
Regular season
Group A
Group B
Results All teams play twice against the teams within their own group and once against the teams from the other group.
Championship playoffs
First round S.P. Tre Fiori 3-1 S.S. Virtus S.P. Cailungo 3-0 A.C. Libertas
Second round F.C. Domagnano 0-0 (pen 5-4) S.P. Cailungo S.S. Folgore/Falciano 0-0 (pen 5-3) S.P. Tre Fiori
Third round S.P. Tre Fiori 2-1 A.C. Libertas S.S. Virtus 2-2 (pen 5-3) S.P. Cailungo
Semifinals S.S. Folgore/Falciano 3-1 F.C. Domagnano S.P. Tre Fiori 1-2 S.S. Virtus
Preliminaryfinal F.C. Domagnano 1-0 S.S. Virtus
Final S.S. Folgore/Falciano 3-1 F.C. Domagnano
References San Marino - List of final tables (RSSSF)