4-hydroxyglutamate transaminase () is an enzyme that catalyzes the reversible chemical reaction
The two substrates of this enzyme characterised from rat liver are (4R)-4-hydroxy-L-glutamic acid and α-ketoglutaric acid. Its products are D-4-hydroxy-2-oxoglutaric acid and L-glutamic acid. It has been suggested that this enzyme is the same as aspartate transaminase.
This enzyme is a transferase, specifically a transaminase, which transfer nitrogenous groups. The systematic name of this enzyme class is 4-hydroxy-L-glutamate:2-oxoglutarate aminotransferase. This enzyme is also called 4-hydroxyglutamate aminotransferase. It participates in arginine and proline metabolism.
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