Alanine-glyoxylate transaminase () is a pyridoxal phosphate-dependent enzyme that catalyzes the chemical reaction
The two substrates of this enzyme characterised from liver and kidney are L-alanine and glyoxylic acid. Its products are pyruvic acid and glycine.
This enzyme is a transferase, specifically a transaminase, which transfer nitrogenous groups. The systematic name of this enzyme class is L-alanine:glyoxylate aminotransferase. Other names in common use include AGT, alanine-glyoxylate aminotransferase, alanine-glyoxylic aminotransferase, and L-alanine-glycine transaminase.
Structural studies As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes , , , , , , and .
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