Formyltetrahydrofolate deformylase () is an enzyme that catalyzes the chemical reaction
The enzyme hydrolyses 10-formyltetrahydrofolate to tetrahydrofolic acid and formic acid. This reaction is part of the metabolism of one-carbon units in plants and other organisms.
This enzyme is a hydrolase, one acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is 10-formyltetrahydrofolate amidohydrolase.
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