The enzyme raucaffricine β-glucosidase () catalyzes the following chemical reaction:

The enzyme characterised from Rauwolfia serpentina species removes the glycoside unit from the indole alkaloid, raucaffricine, to give vomilenine and D-glucose.

This enzyme is a hydrolase, specifically a glycosidase that hydrolyses O- and S-glycosyl compounds. The systematic name of this enzyme class is raucaffricine β-D-glucohydrolase. Other names include raucaffricine β-D-glucosidase, and raucaffricine glucosidase.

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