In enzymology, an alpha-glucuronidase () is an enzyme that catalyzes the chemical reaction
an alpha-D-glucuronoside + H2O an alcohol + D-glucuronate
Thus, the two substrates of this enzyme are alpha-D-glucuronoside and H2O, whereas its two products are alcohol and D-glucuronate.
This enzyme belongs to the family of hydrolases, to be specific those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is alpha-D-glucosiduronate glucuronohydrolase. This enzyme is also called alpha-glucosiduronase.
Structural studies
As of late 2007, 13 structures have been solved for this class of enzymes, with PDB accession codes , , , , , , , , , , , , and .
See also Beta-glucuronidase Glucuronosyl-disulfoglucosamine glucuronidase Glycyrrhizinate beta-glucuronidase
References
Visser, J., Kusters van Someren, M.A., Beldman, G. and Voragen, A.G.J. (Eds.), Xylans and Xylanases, Elsevier, Amsterdam, 1992, p. 213-224.