AMP nucleosidase () is an enzyme that catalyzes the chemical reaction
The enzyme characterised from Azotobacter vinelandiil and Escherichia coli hydrolyses the pyrimidine nucleotide, adenosine monophosphate, to D-ribose 5-phosphate and adenine. The enzyme has been used in a systems engineering approach to the industrial production of purines.
This enzyme is a hydrolase, specifically a glycosylase that hydrolyses N-glycosyl compounds. he systematic name of this enzyme class is AMP phosphoribohydrolase. Other names in common use include adenylate nucleosidase, and adenosine monophosphate nucleosidase.
Structural studies As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes , , , , and .
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