The enzyme S-succinylglutathione hydrolase (EC 3.1.2.13) catalyzes the reaction
The enzyme characterised from human liver hydrolyses S-succinylglutathione to glutathione and succinic acid, which forms the thioester in the starting material.
This enzyme is a hydrolase, specifically one acting on thioester bonds. The systematic name is ''S''-succinylglutathione hydrolase.
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